BioStruct Students

Students at UiO Supervisor Title of thesis
Inger Kristine Olsbu Kristoffer Andersson Structure-Activity Relationship of Heme-Thiolate Proteins: -Specially of Guanidines and N-hydroxyguanidines as substrates of Nitric Oxid Synthase
Åsmund Kaupang Trond Vidar Hansen Molecular modelling/docking of selective ligands for the PPARy nuclear receptor. Synthesis of new antagonists with subsequent testing in cell culture assays.
Zsuzsa Husenica Anne Spurkland TSAd mediated Lck-Itk crosstalk
Marie Lofstad Kristoffer Andersson Structural and spectroscopic studies of oxygen activation and electron transfer in the ribonucleotide reductase and nitric oxide synthase protein systems of Bacillus cereus.
Bie Ekblad Jon Nissen-Meyer Structure-Function Analysis of Class II Bacteriocins (Antimicrobial peptides) and Their Immunity Proteins
Algirdas Grevys Inger Sandlie, Jan Terje Andersen New perspective on IgG function
Kine Marita Knudsen Sand Inger Sandlie FcRn binding and sorting of albumin
Mari Ytre-Arne Bjørn Dalhus Structure-based design of DNA glycosylase inhibitors as adjuvants in cancer therapy
Julia Isabel Tandberg Hanne C. Winther-Larsen, Gareth Griffiths Studies of host-pathogen interactions and development of nanoparticle based vaccines against intracellular bacterial pathogens in aquaculture
Helen V. Thorbjørnsrud Ute Krengel, Michele Cascella Shikimate pathway enzymes – Mechanisms, function, and discovery
Nandini Chauhan Dirk Linke Insights into the Autotransport process of trimeric autotransporter YadA
Nis Valentin L. Nielsen Sandip Kanse, Jens Preben Morth Structure-function analysis of factor VII activation protease with respect to vascular diseases
Daniel Hatlem Dirk Linke, Ute Krengel Bacterial adhesion: Structural characterization of trimeric autotransporters binding to the endothelial extracelluar matrix
Hedda Johannesen Kristoffer Andersson, Hans Petter Hersleth, Marta Hammerstad RNA group III – crystallization and kinetics
Manuel Schweikle Håvard Haugen Targeted drug delivery systems for bone tissue regeneration and remodelling
Ingvild Gudim Hans-Petter Hersleth, Marta Hammerstad, K. Kristoffer Andersson Structural basis for electron transfer in and between redox proteins – recognition, selectivity and flexibility
Joël B. Heim Ute Krengel, Kristian Prydz, Michele Cascella Bacterial toxins – Structure, function and molecular interactions
     
Students at UiB Supervisor Title of thesis
Hans Kristian Leren Bernt Th. Walther Ikke-toksiske eksfolierende endoproteaser
Helene Bustad Johannessen Sverre Sandberg, Aurora Martinez Phenotypic outcome and novel therapies in Acute Intermittent Porphyria
Thomas Karlsson Aurèlia E. Lewis Characterization of altered biomolecular networks in aggressive endometrial cancer and their evaluation as potential therapeutic targets
Maria Teresa Bezem Aurora Martinez Functionalization of nanoparticles with tyrosine hydroxylase. Biotechnological and therapeutic implications
Rhian Morgan Aurèlia E. Lewis Characterisation of altered biomolecular interaction networks in insulin resistance and their evaluation as potential therapeutic targets
Maxim Bril’kov Øyvind Halskau, Rein Aasland, Olena Dobrovolska CW domain specificity and function in histone-tail recognition proteins
Oscar Aubi Catervilla Aurora Martinez Development of novel therapeutic approaches for genetic disorders associated to misfolding
Marianne Goris Thomas Arnesen Dynamic N-terminal acetylation of orgnellar proteins
Morten Govasli Larsen Pål Puntervoll, Øyvind Halskau Structural characterization of the E.coli heat stable toxin (ST) and its interactions with its target receptor and neutralizing antobodies
Ingvill Tolås Mathias Ziegler Characterization of the mechanism behind mitochondrial lysine acetylation
Dorothée Houry Mathias Ziegler The NMNATs: protein structure, oligomerisation and dynamics in the pathophysiology
Arne Raasakka Petri Kursula Structural biology of the myelin membrane
Martin Jakubec Øyvind Halskau Lipids as catalysts of misfolding proteins and peptides
Bojan Krtenic Nathalie Reuter Structure-based enzyme specificity prediction in the N-terminal acetyltransferase family
     
Students at Norwegian University of Life Sciences Supervisor Title of thesis
Adrian Ertsås Naas Phillip Pope The newly discovered Polysaccharide Utilisation Loci linked to multiple cellulotic systems in nature: How does it work?
Piotr Chylenski Vincent Eijsink Developing a highly efficient enzyme coctail, tailored for Borregaard substrates, that abolish microbial contamination problems.
Trine Isaksen Vincent Eijsink Enzyme technology for next generation biofuels
Sophanit Mekasha Vincent Eijsink Bio-refining of chitin- Development of enzymatic methods for singly sugar decomposing of chitin rich bio-mass
Tina Rise Tuveng Vincent Eijsink, Gustav Vaaje-Kolstad Enzymatic degradation and modification of chitin-rich biomasses
Kirill Ovchinnikov Dzung Bao Diep, Helge Holo, Per Eugen Kristiansen Structure-function relationship of bacteriocins
Hai Chi Dzung Bao Diep, Helge Holo Mode of action of novel bacteriocins, isolated from milk, against target cells
Giusi Minniti Vincent Eijsink, Gustav Vaaje-Kolstad Studies of pathogenic species in Salmon salar skin mucus – structural and functional characterization of mucin active enzymes
Ingvild Isaksen Åsmund Kjendseth Røhr, Morten Sørlie Resolving molecular mechanisms of biomass degrading enzymes through a combined computational and experimental approach
Marianne Slang Jensen Vincent Eijsink, Gustav Vaaje-Kolstad Enzyme development for biorefining of Norwegian biomass
Silje Benedicte Lorentzen Vincent Eijsink Chitotex – Development and production of new insect chitosan and chitosan based functional coatings for textiles
Nina Zoric Dag Inge Våge Genetic and functional studies of flesh pigmentation in salmon
     
Students at NTNU Supervisor Title of thesis
Ida Ericsson Bodil Kavli/Hans Krokan UNG2 and AID – roles in immunity
Marianne Øksnes Dalheim Bjørn Erik Christensen Chemically modified polysaccharides as biomaterials
Renana Rabe Geir Slupphaug Interaction partners and post translational modifications of DNA-Uracil-glycosylase 2 (UNG2) in antibody diversification processes
Annalucia Stanisci Gudmund Skjåk-Bræk Functional characterization and design of alginate modifying enzymes
Georg Kopplin Kjell Morten Vårum Marine polysaccharides – characterization and advanced applications
Gaston Courtade Finn L. Aachmann, Trygve Brautaset Structural and functional investigation of lytic polysaccharide monooxygenase (LPMO) by NMR spectroscopy
Line Aanerud Omtvedt Finn L. Aachmann, Berit L. Strand Chemical and enzymatic modification of Biopolymers
     
Students at UiT Supervisor Title of thesis
Aili Sarre Arne Smalås Functional and structural biology studies of DNA repair proteins from the radiation resistant bacterium Deinococcus radiodurans
Dilip Narayanan Rick Engh Focussed chemical library design by ATP-site specific parameterization: crystallography, biophysical methods, and cheminformatics
Sunniva K. Thode Peik Haugen Global responses of Aliivibrio salmonicida to iron limiting conditions
Kristel Berg Ingar Leiros Structural and functional characterization of the Ferric Uptake Regulator (FUR) from Aliivibrio Salmonicida
Balmukund Thakkar Rick Engh Design, Synthesis and Bioactivity studies of diversity oriented target focused libraries of compounds, initially based on piperazine-2,5-dione, and other chemical scaffolds as potential inhibitors of protein-kinase and other targets
Ilona Urbarova Steinar Johansen Exploring transcriptomes of cold-adapted anthozoans
Kazi Asraful Alam Rick Engh Structural and flexibility determinants of Aurora kinase ligand binding
Sundus Anette Bayer Design, Synthesis and Bioactivity of Target Focused Libraries of Compaounds Based on Triazole, Tetrazole and Related Scaffolds as Potential Inhibitors of Metallo Beta-lactamases (MBLs) and other Relavant Targets
Davide Michetti Bjørn Olav Brandsdal Cold-adapted enzymes: a paradigm for Designing enzymes with novel features
Miriam Khider Nils Peder Willassen Cloning, characterization and expression analysis of PUFA operon from Shewanella Olleyana, with focua on EPA and DHA production in Vibrio Wodanis
Espen Mikal Robertsen Nils Peder Willassen, Peik Haugen, Lars Ailo Bongo METApipe- Automated pipeline analysis
Anna Subbotina Aina Westrheim Ravna, Georg Sager Pharmacology of ABC transporters
Marie-Josèe Haglund Halsør Arne O. Smalås, Inger Lin Uttakleiv Ræder, Bjørn Altermark, Ulli Rothweiler Enzymes for production of sialic acids and derivates
Amudha D. Maharajan Nils Peder Willassen, Hilde Hansen, Erik Hjerde, and Ketil Åsbakk How do winter ulcer pathogens control its environment?
Linn Marie Evenseth Ingebrigt Sylte Structure, function, and ligand interactions of antidepressant drug targets
Marc Boomgarden Jørn Hansen, Rick Engh Bioactive Heterocycle Libraries for Drug Discovery
Tor Olav Berg Arne Smalås, Inger Lin U. Ræder Biocatalytic production of sialic acids and derivates – with focus on sialic acids aldolases and mutarotases
Aelita G. V. Konstantinell Ugo Moens, Baldur Sveinbjørnsson The reciprocity of inflammation and virus in tumorgenesis
Ravdna Sarre Johan Isaksson Drug Discovery using Nuclear Magnetic Resonance spectroscopy on the basis of marine bioprospecting
Kashif Rasheed Baldur Sveinbjørnsson, Ugo Moens Reciprocity of Inflammation and Virus in Tumorigenesis
     
Students at UiS Supervisor Title of thesis
Marina Alexeeva Svein Bjelland DNA base excision repair enzymes: novel functions, regulations, and variation in normal and cancer cells
Almaz Nigatu Tesfahun Svein Bjelland Novel functions in DNA excision repair
Stefanie Lackner Lutz Eichacker Isolation and characterisation of functional protein complexes