Carbamates from CO2

NordCO2 member Prof. Timo Repo and his co-workers have reported a facile synthesis of cyclic carbamates from amino alcohols and CO2:

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Tosyl-assisted cyclization of carbon dioxide and amino alcohols in the presence of an external base. The carbamate species must be formed first and stabilized to avoid the competing N-tosylation reaction, which prevents the formation of the desired product.