Carbamates from CO2

NordCO2 member Prof. Timo Repo and his co-workers have reported a facile synthesis of cyclic carbamates from amino alcohols and CO2: http://pubs.rsc.org/en/content/articlepdf/2018/cc/c8cc00636a

The article is Open access and free to read for everyone.

image file: c8cc00636a-f1.tif
Tosyl-assisted cyclization of carbon dioxide and amino alcohols in the presence of an external base. The carbamate species must be formed first and stabilized to avoid the competing N-tosylation reaction, which prevents the formation of the desired product.