Project leader John Sigurd Svendsen
Group leader for Organic Chemistry
Project leader for DigiBiotics and AntiBioSpec
CSO for AmiCoat and PharmaSum Therapeutics
WP1: Biodiscovery
Biodiscovery of novel macrocyclic compounds from Arctic marine sources. Read more here.
Work-package leader: Jeanette H. Andersen
PhD Student: Marte Jenssen
Post Doc: Teppo Rämä
WP2: Organic synthesis
Synthesis of derivatives to improve the efficacy and ADMET properties of discovered macrocycles using organic- and bio-synthesis. Read more here.
Work-package leader: John Sigurd Svendsen
PhD Student: Tone Kristoffersen
PhD Student AmiCoat: Eskil André Karlsen
Post Doc: Marianne Hagensen Paulsen
Post Doc: Vacant position
WP3: Optical spectroscopy and ab initio calculations
Characterization of Natural Compounds absolute and relative configurations using Optical Methods and ab initio calculations. Read more here.
Work-package leader: Kenneth Ruud
PhD Student: Karolina Solheimseid Eikås
WP4: NMR spectroscopy
Structure elucidation of Natural compounds, determination of relative stereochemistry and conformation analysis using NMR spectroscopy. Characterization of membrane interactions using nanodiscs. Read more here.
Work-package leader: Johan Isaksson
PhD Student: Phil Rainsford
PhD Student: Fredrik Garnås Rylandsholm
PhD Student: Ravdna Sarre
WP5: Molecular dynamics simulations
Computer simulations of membrane models and their interactions with macrocycles using large scale molecular dynamics. Read more here.
Work-package leader: Bjørn Olav Brandsdal
PhD Student: Laura Liikanen
WP6: Activity and resistance studies
Bio-activity testing using clinical isolates and determination of resistance development propensity and host determinants. Read more here.
Work-package leader: Johanna E. Sollid
PhD Student: Eric Juskewitz
Post Doc: Ekaterina Mishchenko
Logo: Johan Isaksson. WP1 photo: Marte Jenssen. WP2: photo-Marianne Hagensen Paulsen, biotage.com. WP3 photo: Karolina Solheimslid Eikås. WP4: photoand spectra-Marianne H. Paulsen Nanodisc: http://www.fz-juelich.de/ics/ics-6/EN/Research/Themen/04Nanodiscs/WP5: Ravnda A. Sarre WP6: Photo – Hanna-Kirsti Leiros EUCAST: Beco, L., et al. (2013). Vet Rec172(3): 72-78.