{"id":452,"date":"2020-08-23T22:05:21","date_gmt":"2020-08-23T20:05:21","guid":{"rendered":"https:\/\/site.uit.no\/bayerlab\/?page_id=452"},"modified":"2026-04-16T21:28:31","modified_gmt":"2026-04-16T19:28:31","slug":"natural-product-chemistry","status":"publish","type":"page","link":"https:\/\/site.uit.no\/bayerlab\/research\/natural-product-chemistry\/","title":{"rendered":"Natural product chemistry"},"content":{"rendered":"\n

The society relies on a continuous development of new drugs, either to replace older and less efficient drugs, or even more important, to address clinical needs that are unmet today. \u201cNatural products play an important role in the development of drugs and it is estimated that approximately 80% of prescribed drugs today are either natural products or have been derived from natural products. Our work focuses on the development of efficient synthetic strategies of bioactive natural product and systematic modification of the original structure to gain an understanding of the structural features that are important for the desired biological activity.<\/p>\n\n\n\n

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Related publications:\u00a0<\/strong>
\u2666\u00a0J. Org. Chem. 2025<\/strong>, 13597. Stereocontrolled and Adaptable Synthesis of (\u2013)-Aspergilone A via the Key Intermediate (+)-Phenol A. doi: 10.1021\/acs.joc.5c01650<\/a><\/p>\n\n\n\n

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\u2666\u00a0Synlett 2018<\/strong>, 1303. Aldol condensations on a 3-alkylidene-2,5-diketopiperazine \u2013\u00a0 synthesis of two marine natural products. <\/em>doi: 10.1055\/s-0036-1591755<\/a>
\u2666\u00a0Org. Biomol. Chem. 2016<\/strong>, 7570. Efficient and scalable synthesis of \u03b1,\u03b1-disubstituted \u03b2\u2013amino amides. <\/em>doi:\u00a0<\/strong>10.1039\/C6OB01219A<\/a>
\u2666\u00a0Org. Lett. 2015<\/strong>, 122. A Concise Total Synthesis of Breitfussin A and B. doi:\u00a010.1021\/ol503348n<\/a><\/em><\/p>\n\n\n\n

\"\"<\/figure>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

The society relies on a continuous development of new drugs, either to replace older and less efficient drugs, or even more important, to address clinical needs that are unmet today. \u201cNatural products play an important role in the development of … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":826,"featured_media":0,"parent":12,"menu_order":3,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-452","page","type-page","status-publish","hentry"],"yoast_head":"\nNatural product chemistry - BAYER LAB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/site.uit.no\/bayerlab\/research\/natural-product-chemistry\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Natural product chemistry - BAYER LAB\" \/>\n<meta property=\"og:description\" content=\"The society relies on a continuous development of new drugs, either to replace older and less efficient drugs, or even more important, to address clinical needs that are unmet today. \u201cNatural products play an important role in the development of … Continue reading →\" \/>\n<meta property=\"og:url\" content=\"https:\/\/site.uit.no\/bayerlab\/research\/natural-product-chemistry\/\" \/>\n<meta property=\"og:site_name\" content=\"BAYER LAB\" \/>\n<meta property=\"article:modified_time\" content=\"2026-04-16T19:28:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/pubs.acs.org\/cms\/10.1021\/acs.joc.5c01650\/asset\/images\/large\/jo5c01650_0005.jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/bayerlab\\\/research\\\/natural-product-chemistry\\\/\",\"url\":\"https:\\\/\\\/site.uit.no\\\/bayerlab\\\/research\\\/natural-product-chemistry\\\/\",\"name\":\"Natural product chemistry - 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