{"id":3445,"date":"2024-04-23T10:31:00","date_gmt":"2024-04-23T08:31:00","guid":{"rendered":"https:\/\/site.uit.no\/nordco2\/?p=3445"},"modified":"2024-10-11T12:19:44","modified_gmt":"2024-10-11T10:19:44","slug":"research-article-uit-8","status":"publish","type":"post","link":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/","title":{"rendered":"Research Article: UiT"},"content":{"rendered":"\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\/adsc202301285-toc-0001-m.jpg\" alt=\"Graphical Abstract\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Title:<\/strong><br><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adsc.202301285\" data-type=\"link\" data-id=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/adsc.202301285\">Asymmetric Boracarboxylation of Styrenes Using Carbon Dioxide<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Abstract:<\/strong><br>The boracarboxylation reaction has potential for the production of natural products and drug candidates, but the development of an asymmetric version of this transformation is challenging. We report an enantioselective boracarboxylation of styrenes, enabled by a copper catalyst containing chiral phosphines. Our experimental conditions provide yields between 31\u201376% and enantiomeric ratios from 80:20 up to 98:2 for electron-rich styrenes. Oxidation of a boracarboxylation product gives (<em>S<\/em>)-tropic acid, an intermediate towards several tropane alkaloids. A computational analysis of the mechanistic details shows a complex pattern of competing reaction pathways, highlighting challenges encountered when developing asymmetric reactions using CO<sub>2<\/sub>.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Find a list of publications by\u00a0NordCO<sub>2<\/sub>\u00a0members on our\u00a0<a href=\"https:\/\/site.uit.no\/nordco2\/publications\/\">Publications<\/a>\u00a0page\u00a0\ud83d\ude42<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Title:Asymmetric Boracarboxylation of Styrenes Using Carbon Dioxide Abstract:The boracarboxylation reaction has potential for the production of natural products and drug candidates, but the development of &hellip;<\/p>\n","protected":false},"author":514,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"image","meta":{"ngg_post_thumbnail":0,"footnotes":""},"categories":[8],"tags":[],"class_list":["post-3445","post","type-post","status-publish","format-image","hentry","category-research","post_format-post-format-image"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Research Article: UiT - Nordic Consortium for CO2 Conversion<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Research Article: UiT - Nordic Consortium for CO2 Conversion\" \/>\n<meta property=\"og:description\" content=\"Title:Asymmetric Boracarboxylation of Styrenes Using Carbon Dioxide Abstract:The boracarboxylation reaction has potential for the production of natural products and drug candidates, but the development of &hellip;\" \/>\n<meta property=\"og:url\" content=\"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/\" \/>\n<meta property=\"og:site_name\" content=\"Nordic Consortium for CO2 Conversion\" \/>\n<meta property=\"article:published_time\" content=\"2024-04-23T08:31:00+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-10-11T10:19:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\/adsc202301285-toc-0001-m.jpg\" \/>\n<meta name=\"author\" content=\"joehh\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"joehh\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/\"},\"author\":{\"name\":\"joehh\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#\\\/schema\\\/person\\\/993cf3b27a956c23c8da21d29fe6bd7c\"},\"headline\":\"Research Article: UiT\",\"datePublished\":\"2024-04-23T08:31:00+00:00\",\"dateModified\":\"2024-10-11T10:19:44+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/\"},\"wordCount\":119,\"publisher\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/onlinelibrary.wiley.com\\\/cms\\\/asset\\\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\\\/adsc202301285-toc-0001-m.jpg\",\"articleSection\":[\"Research\"],\"inLanguage\":\"en-GB\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/\",\"url\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/\",\"name\":\"Research Article: UiT - Nordic Consortium for CO2 Conversion\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/onlinelibrary.wiley.com\\\/cms\\\/asset\\\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\\\/adsc202301285-toc-0001-m.jpg\",\"datePublished\":\"2024-04-23T08:31:00+00:00\",\"dateModified\":\"2024-10-11T10:19:44+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/#breadcrumb\"},\"inLanguage\":\"en-GB\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/#primaryimage\",\"url\":\"https:\\\/\\\/onlinelibrary.wiley.com\\\/cms\\\/asset\\\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\\\/adsc202301285-toc-0001-m.jpg\",\"contentUrl\":\"https:\\\/\\\/onlinelibrary.wiley.com\\\/cms\\\/asset\\\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\\\/adsc202301285-toc-0001-m.jpg\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/2024\\\/04\\\/23\\\/research-article-uit-8\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Research Article: UiT\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#website\",\"url\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/\",\"name\":\"Nordic Consortium for CO2 Conversion\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-GB\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#organization\",\"name\":\"Nordic Consortium for CO2 Conversion\",\"url\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/wp-content\\\/uploads\\\/sites\\\/344\\\/2018\\\/01\\\/cropped-logonewnordco2_2-2.png\",\"contentUrl\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/wp-content\\\/uploads\\\/sites\\\/344\\\/2018\\\/01\\\/cropped-logonewnordco2_2-2.png\",\"width\":174,\"height\":96,\"caption\":\"Nordic Consortium for CO2 Conversion\"},\"image\":{\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#\\\/schema\\\/logo\\\/image\\\/\"}},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/#\\\/schema\\\/person\\\/993cf3b27a956c23c8da21d29fe6bd7c\",\"name\":\"joehh\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-GB\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41b39828da26f7150fc97cb70bc12710fe106a864e4f01c116292a086677dd77?s=96&d=blank&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41b39828da26f7150fc97cb70bc12710fe106a864e4f01c116292a086677dd77?s=96&d=blank&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/41b39828da26f7150fc97cb70bc12710fe106a864e4f01c116292a086677dd77?s=96&d=blank&r=g\",\"caption\":\"joehh\"},\"url\":\"https:\\\/\\\/site.uit.no\\\/nordco2\\\/author\\\/joehh\\\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Research Article: UiT - Nordic Consortium for CO2 Conversion","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/","og_locale":"en_GB","og_type":"article","og_title":"Research Article: UiT - Nordic Consortium for CO2 Conversion","og_description":"Title:Asymmetric Boracarboxylation of Styrenes Using Carbon Dioxide Abstract:The boracarboxylation reaction has potential for the production of natural products and drug candidates, but the development of &hellip;","og_url":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/","og_site_name":"Nordic Consortium for CO2 Conversion","article_published_time":"2024-04-23T08:31:00+00:00","article_modified_time":"2024-10-11T10:19:44+00:00","og_image":[{"url":"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\/adsc202301285-toc-0001-m.jpg","type":"","width":"","height":""}],"author":"joehh","twitter_card":"summary_large_image","twitter_misc":{"Written by":"joehh","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/#article","isPartOf":{"@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/"},"author":{"name":"joehh","@id":"https:\/\/site.uit.no\/nordco2\/#\/schema\/person\/993cf3b27a956c23c8da21d29fe6bd7c"},"headline":"Research Article: UiT","datePublished":"2024-04-23T08:31:00+00:00","dateModified":"2024-10-11T10:19:44+00:00","mainEntityOfPage":{"@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/"},"wordCount":119,"publisher":{"@id":"https:\/\/site.uit.no\/nordco2\/#organization"},"image":{"@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/#primaryimage"},"thumbnailUrl":"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\/adsc202301285-toc-0001-m.jpg","articleSection":["Research"],"inLanguage":"en-GB"},{"@type":"WebPage","@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/","url":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/","name":"Research Article: UiT - Nordic Consortium for CO2 Conversion","isPartOf":{"@id":"https:\/\/site.uit.no\/nordco2\/#website"},"primaryImageOfPage":{"@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/#primaryimage"},"image":{"@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/#primaryimage"},"thumbnailUrl":"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\/adsc202301285-toc-0001-m.jpg","datePublished":"2024-04-23T08:31:00+00:00","dateModified":"2024-10-11T10:19:44+00:00","breadcrumb":{"@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/#breadcrumb"},"inLanguage":"en-GB","potentialAction":[{"@type":"ReadAction","target":["https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/"]}]},{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/#primaryimage","url":"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\/adsc202301285-toc-0001-m.jpg","contentUrl":"https:\/\/onlinelibrary.wiley.com\/cms\/asset\/718e8b1b-a5dd-4ff1-bc2e-539aa8606888\/adsc202301285-toc-0001-m.jpg"},{"@type":"BreadcrumbList","@id":"https:\/\/site.uit.no\/nordco2\/2024\/04\/23\/research-article-uit-8\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/site.uit.no\/nordco2\/"},{"@type":"ListItem","position":2,"name":"Research Article: UiT"}]},{"@type":"WebSite","@id":"https:\/\/site.uit.no\/nordco2\/#website","url":"https:\/\/site.uit.no\/nordco2\/","name":"Nordic Consortium for CO2 Conversion","description":"","publisher":{"@id":"https:\/\/site.uit.no\/nordco2\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/site.uit.no\/nordco2\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-GB"},{"@type":"Organization","@id":"https:\/\/site.uit.no\/nordco2\/#organization","name":"Nordic Consortium for CO2 Conversion","url":"https:\/\/site.uit.no\/nordco2\/","logo":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/site.uit.no\/nordco2\/#\/schema\/logo\/image\/","url":"https:\/\/site.uit.no\/nordco2\/wp-content\/uploads\/sites\/344\/2018\/01\/cropped-logonewnordco2_2-2.png","contentUrl":"https:\/\/site.uit.no\/nordco2\/wp-content\/uploads\/sites\/344\/2018\/01\/cropped-logonewnordco2_2-2.png","width":174,"height":96,"caption":"Nordic Consortium for CO2 Conversion"},"image":{"@id":"https:\/\/site.uit.no\/nordco2\/#\/schema\/logo\/image\/"}},{"@type":"Person","@id":"https:\/\/site.uit.no\/nordco2\/#\/schema\/person\/993cf3b27a956c23c8da21d29fe6bd7c","name":"joehh","image":{"@type":"ImageObject","inLanguage":"en-GB","@id":"https:\/\/secure.gravatar.com\/avatar\/41b39828da26f7150fc97cb70bc12710fe106a864e4f01c116292a086677dd77?s=96&d=blank&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/41b39828da26f7150fc97cb70bc12710fe106a864e4f01c116292a086677dd77?s=96&d=blank&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/41b39828da26f7150fc97cb70bc12710fe106a864e4f01c116292a086677dd77?s=96&d=blank&r=g","caption":"joehh"},"url":"https:\/\/site.uit.no\/nordco2\/author\/joehh\/"}]}},"_links":{"self":[{"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/posts\/3445","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/users\/514"}],"replies":[{"embeddable":true,"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/comments?post=3445"}],"version-history":[{"count":1,"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/posts\/3445\/revisions"}],"predecessor-version":[{"id":3446,"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/posts\/3445\/revisions\/3446"}],"wp:attachment":[{"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/media?parent=3445"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/categories?post=3445"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/site.uit.no\/nordco2\/wp-json\/wp\/v2\/tags?post=3445"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}