Economic burden of venous thromboembolism in cancer patients

By Ina I. Høiland, PhD student at TREC

Venous thromboembolism (VTE) is a common complication in cancer patients, and cancer patients are at increased risk for recurrent venous thromboembolism. Despite the well-established association between cancer and venous thromboembolism, there are few studies about the economic burden of venous thromboembolism in cancer patients. To asses, this a group at the Department of Health Sciences Research, Mayo Clinic, Rochester, USA recently conducted a population-based cohort study to estimate the medical costs associated with cancer associated VTE. Continue reading

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New antidote for factor Xa inhibitors

By Timofey Sovershaev, PhD student at TREC

Thrombotic complications are a serious risk in several disorders, including atrial fibrillation, venous thromboembolism and many others. Traditionally, vitamin K antagonists (warfarin) or low-molecular weight heparins were used to prevent such complications. During the last years, a novel drug class, factor Xa inhibitors, has been incorporated into clinical practice, as these drugs have the potential to be safer and easier to use than the traditional vitamin K inhibitors. However, until recently, there was no agent to reverse their effects. Continue reading

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How does clot lysis time affect risk of a first or recurrent venous thrombosis?

By Robin Liang, PhD in TREC

There is a continuous search for finding laboratory markers that are associated with an increased risk of venous thromboembolism (VTE). While the focus has been mainly on procoagulant pathways that form the clot, there have been relatively few studies that

examine fibrinolytic (clot-breaking) activity in relation to the risk of VTE. Continue reading

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Does the use of new oral contraceptives increase your risk of blood cloth formation?

By Nadia Arshad, PhD in TREC

p-pillerA study published in British Medical Journal on the 26th of May 2015 have looked at the association between usage of  oral contraceptives, and the risk of developing blood clots, also called venous thromboembolism (VTE), in a large registry-based study conducted in the United Kingdom in 2001-2013. Continue reading

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