A new target for prevention of blood clots?

Av Robin Liang
Stipendiat ved TREC

Platelets play a role in the formation of blood clots, but the impact of their different receptors is still unclear. CLEC-2 is among the receptors found on platelets, and is important in maintaining the normal state of vessels in the presence of inflammation. As deep vein thrombosis (DVT) is a thromboinflammatory disorder involving a blood clot in the deep veins of the leg, CLEC-2 could be a receptor of interest in DVT research.

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The risk of recurrent VTE is high in the first 2-months after stopping anticoagulants

By Nadia Arshad, PhD at TREC

Venous thrombosis (VTE) is a common term for blood clots in the deep veins of the body and/or in the lungs. Vitamin K antagonists (VKA) are within the group of blood-thinning medicines called anticoagulants, and are used to treat blood clots. A study accepted for publication in the Journal of Thrombosis and Hemostasis on 28th March 2016, discussed the risk of VTE recurrence (rVTE) during the first 2-months after stopping anticoagulants. Continue reading

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Inter-rater agreement between professional-rated and patient-rated scores of the Villalta scale for evaluation of the post-thrombotic syndrome

By Trond Isaksen, PhD student TRECtrond i artikkel bilde

The Post-thrombotic syndrome (PTS) refers to chronic symptoms and signs following a blood clot in the deep veins. The Villalta scale measure the severity of PTS, which vary from none to disabling symptoms and signs like pain, swelling and ulcers. No effective treatment for PTS is available and progress will depend on research. Continue reading

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The Secret Ingredient

By Søren Beck Jensen, postdoc TREC

søren6Do you experiment in your kitchen at home? In the TREC research laboratory, we experiment every day to gain new knowledge about how blood coagulation works. The result we saw yesterday shows that we could not manipulate the blood’s ability to form clots by adding a secret ingredient. Maybe we need to add more of it? Continue reading

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